Instruments

The 3500 Genetic Analyzer is a fluorescence based DNA analysis machine which uses capillary electrophoresis technology. The 8-capillary sequencing instrument specifically designed to support the demanding performance needs of validated and process controlled environments, while retaining the unsurpassed application versatility that life science researchers expect.

The Single-line, 505 nm, solid-state, long-life laser that utilizes a standard power supply and requires no heat-removal ducting with powerful, integrated data collection and primary analysis software provides real-time assessment of data quality. The Radio frequency identification (RFID) technology tracks key consumables data and records administrativeinformation and Advanced multiplexing capabilities for DNA fragment analysis with up to six unique dyes. Unrivaled application flexibility-one array and one polymer are used for most applications with simple setup, operation and maintenance-the easiest-to-run, easiest-to-own DNA sequencer to date.Buffers and conditioning reagent consumables: Similar to the 3500 System polymer pouches, the 3500 Series Genetic Analyzer Cathode Buffer, Anode Buffer, and Conditioning Reagent are designed for ready-to-use, load-and-run installation. Consumable containers are disposed of when the maximum number of samples has been processed.

Specifications

Analysis Software:GeneMapper® Software, Sequencing Analysis Software, Variant Reporter® Software.Read Length: >850 bp using a 50 cm capillary and POP-7™ polymer.Capillary Length: 50 cm.Compatible Polymer: POP-7™. Current Limit: 15 amps.Format: 8-well strips, 96-well plate. Number of Capillaries: 8 Capillaries. Laser: Long-life, single-line 505 nm solid-state laser excitation source. Electrophoresis voltage: Up to 20 kV. Oven temperature: Active temperature control from 18°C to 70°C. Operating environment: Temperature: 15°C–30°C (room temperature should not fluctuate more than ±2°C during an instrument run) Humidity: 20–80% (noncondensing). Main power voltage: 100–240 V ±10% 50–60 Hz ±10%. Current: Maximum: 15 A. Maximum power dissipation: 417 VA, 371 W (approximate, not including computer and monitor). Dimensions: Width (closed door): 61 cm Width (open door): 122 cm Depth: 61 cm Height: 72 cm Weight: 82 kg (approximately).

Key applications

Aneuploidy Detection, Melanoma detection, Detect Sequence Variants in the BRCA1 and BRCA2 Genes, DNA Resequencing Analysis of X-linked Variants,genotyping.