Biotechnology

 

1. Brief History of Department:  

The University of Mysore established Department of Studies in Applied Botany and Seed Pathology (DAB) by integrating the ICAR supported Downy Mildew Research Laboratory (DMRL), UGC-SAP-DRS programme on Seed Pathology and M.Phil in Seed Pathology programme which were formerly housed in the Department of Studies in Botany.  DAB introduced M.Sc in Biotechnology in 1992, which was recognized under DBT-HRD programme of Government of India in 1998.  The Department proved its potential as a premier training and research center by attracting grants from various national funding agencies like UGC, ICAR, DBT, and DST, and international agencies like DANIDA, EEC etc.  In the last 15 years, the department has generated INR 20 crores (US$ 4 million).

 

M.Phil. programme in Seed Pathology (now Seed Technology) was initiated by the efforts of Dr. Paul Neergaard and Dr. S. B. Mathur, Director of DGISP in the year 1980.  Dr. Paul Neergaard visited the department as Visiting Professor under Sir M. Visweswaraiah Chair and started the M.Phil. course.  With the support of DANIDA and DSHC the department is now recognized as Asian Seed Health Center to coordinate the training and research activities in seed health for the Asian region.

 

The DOS in Applied Botany & Seed Pathology was renamed as DOS in Biotechnology in 2009 by integrating all the courses and research activities and the faculty resources

 

2. Departmental research activities:

Thrust Areas of Research

  • Molecular Plant Pathology
  • Downy mildew of pearl millet: Field screening, host-pathogen interactions, molecular variability of the pathogen, resistance gene characterization, systemic acquired resistance
  • Seed Health: Testing for seed-borne pathogens, molecular characterization and sequence database, molecular diagnostics
  • Biopesticides: Identification and characterization of biocontrol agents, mass culturing formulations, field applications.
  • Mycotoxins: Molecular characterization of toxigenic fungi, analysis, biocontrol
  • Molecular Diversity and development of molecular markers for medicinal plants, genome characterization
  • Bioprospecting of Medicinal Plants/ endophytes
  • Molecular oncology: Drug discovery and validation for anticancer and antiinflammatory therapy
  • Glycobiology: Glyconjugates from colostrum for treatment of diseases

The department is operating the 'Mysore Centre' of the All India Coordinated Pearl millet Improvement Project (AICPMP) of the Indian Council of Agricultural Research (ICAR). Under this programme Biology and management of downy mildew of pearl millet disease is in progress: Field screening, host-pathogen interactions, molecular variability of the pathogen, resistance gene characterization, systemic acquired resistance, and biological control of the downy mildew disease - Prof. H. Shekar Shetty after his superannuation is placed in charge of this ICAR- AICPMIP programme.

3. Status of the Department (FIST/SAP/DRS)

Sl. No.

Status

Phase

Thrust Area

1

UGC-SAP-DSA

I Phase

2007-2012

o   Molecular Plant Pathology

o   Bioprospecting of medicinal plants and microbes

2

DST-FIST

II Phase

2010-2015

-

4. Chairs/Fellowship/Medals (if any)

  • Dr Paul Neergaurd Gold Medal for securing 1st rank in M.Phil Seed Technology
  • Dr S B Mathur Gold Medal for securing 1st rank in M.Sc Biotechnology
  • Applied Botany Decennial Year Gold Medal for securing 1st rank in M.Sc Biotechnology
  • Prof H Shekar Shetty Felicitation Committee Endowment Gold Medal for securing 1st rank in M.Sc Biotechnology
  • Prof. S. Honnaiah Memorial Gold Medal for securing 1st rank in M.Sc Biotechnology
  • Prof. K. M. Safeulla Memorial Gold Medal for securing 1st rank in M.Sc Biotechnology
  • Prof. H. Shekar Shetty Endowment Lecture instituted by M/s. Pioneer Overseas Corporation (A Du Pont Company, Hyderabad)
  • Prof. Paul Neergaard and Prof. Viggo Smedegaard Petersen Endowment Lecture in the area of Biotechnology.

  5. Awards/Honors received by individual Teachers:

    Prof. H. S. Prakash

  • Fellow of National Academy of Agricultural Sciences (NAAS)- 2011
  • Team leader - Terminal evaluation of UNDP-FAO-GOI Programme on quarantine facilities
  • Member of Committee for State Seed Certification facility strengthening
  • Member of ISTA- World Group of Virologists
  • Member of National Project Steering Committee for International Project on Coffee Leaf Rust funded by International Coffee Organization (ICO) and Common Funds for Commodity (CFC)
  • Chairman of Technical Session on "Systematic - Virus", American Phytopathological Society meeting held at Raleigh, USA, July 28-Aug 1, 2009
  • Advisory committee member of Institute of Biotechnology & Allied Sciences Training & Research Institute, Sikar, Rajasthan

Prof. Bharathi P. Salimath

  • Young Scientist Award, 1995 Karnataka State for Advancement of Science, Karnataka.
  • Dr. Veerendra B. Kamath Award, 1996, Indian Association For Cancer Research.
  • Kalpana Chawla Young Women Scientist Award - 2004 instituted by Karnataka Council for S & T
  • Member, PAC, (Health Sciences), DST (2005-08);
  • Member, PAC (Life Sciences), DST (2003-05; 05-07)
  • Member NAAC, UGC, 2007-08
  • Member, Project Review & Monitoring Committee (PRMC) for the Project on "Information Support System in Science and Mathematics for Rural Higher Secondary Schools". 2008-2010
  • Department of Biotechnology, Government of India, Overseas Fellowship- 2008
  • Rashtriya Gaurav Award- 2009
  • Best Citizen of India Award- 2010

Prof. S. R. Niranjana

  • Fellow of National Academy of Agricultural Sciences (NAAS)- 2012
  • Sir. C. V. Raman Young Scientist Award by Karnataka Council for S & T-2009
  • Member, PAC, (Biocontrol), DBT (2012-15)
  • PP Singhal memorial Pesticides India Award-2007 instituted by ISMPP
  • V.P. Bhide Memorial Lecture Award- 2004 instituted by ISMPP
  • Fellow of Indian Society of Mycology and Plant Pathology
  • Zonal president, Indian Phytopathological Society- 2006-07
  • Indian Phytopathological Society Best paper Award - 2007
  • Seed Health in Agricultural Development Best paper Award - 2008
  • P.R. Verma memorial Award - 2008
  • Member NAAC, UGC, 2009-10

Dr. S. Umesha

  • Prof. K. S. Jagadeeshchandra Young Scientist Award for Plant Sciences, 2001-2002
  • Zonal Councillor, Indian Phytopathological Society- 2006-07
  • DBT Overseas Associateship 2006-07
  • Elected, Plant Sciences - Sectional Committee Member, for south zone of Indian Science Congress Association - 2009-10, Kolkata, India.
  • Fellow Member, International Society of Biotechnology, India

Dr. K. Ramachandra Kini

  • Young Scientist Award in 86th Indian Science Congress, 1999 
  • BOYSCAST Fellowship 2006-07
  • Best Poster Award at SHAD-2008
  • Prof. H. C Dube Outstanding Young Scientist Award-2012, instituted by Indian Society of Mycology & Plant Pathology

Prof. H. Shekar Shetty

  • OM PRAKASH BHASIN AWARD for Science and Technology, 1997-1998
  • Fellow of Indian Academy of Sciences in 1997, Fellow of National Academy of Agricultural Sciences in 1998, Fellow of National Academy of Sciences in 2002
  • Member, PAC, Plant Sciences, DST (2001-2003), GM crop Monitoring and Evaluation Committee, DBT
  • Member of the Crop Science Panel, ICAR, 1999-2002, Crop Variety Releasing Committee
  • Chaudhury Devi Lal Best Coordinated Research Project Award to AICPMIP (2004)

  6. Individual teachers ongoing research projects:

 

Name of the Project

Name of the Principal

Investigator/ Coordinator

Funding

Agency

Total Grant

Rs.

in lakhs

Duration with Years

1.       Asian Centre for Training and Research in Seed Health Testing and Seed-Borne Disease Management

Prof. H. S. Prakash (PI)

Prof. H. Shekar Shetty (CoPI)

Prof. S. R. Niranjana (CoPI)

Dr. K. R. Kini (CoPI)

Dr. S. Umesha (CoPI)

DANIDA

Denmark

180

2001 -2011

2.       UGC-SAP-DSA Programme

Prof. H. S. Prakash

UGC

71.2

2007-2012

3.       DST-FIST

Dr. S. R. Niranjana

Prof. H. S. Prakash

Prof. Bharathi.P Salimath

 

DST

70.0

2010-2015

4. Characterization of buffcalo colostrums glycoconjugate to determine their biological activity to use as neonatal food additive.

Dr. H. S. Aparna

UGC

9.42

2007-2010

5.       Biological control of Mycotoxins

Prof. S. R. Niranjana

DBT

42.5

2008-2011

6.       Screening of bioactive compounds from indigenous medicinal plant against downy mildew disease of sunflower.

Prof. S. R. Niranjana

UGC

9.41

2010-1013

7.       Characterization, diagnosis and management of tobacco streak ilarvirus.

Prof. H. S. Prakash

UGC

4.80

2010-2013

8.       Cell culture system for the production of chemotherapeutics fromTinospora cordifolia

Dr. Geetha N. P

UOM

02

2009-2011

9.       MAP Kinases in pearl millet defense response against downy mildew

Dr. K. Ramachandra Kini

UGC

10.6

2009-2012

10.    Development of PCR-SSCP technique for the specific diagnosis of bacterial spot and wilt pathogens in tomato

Dr. S. Umesha

UGC

11.28

2009-2012

11.    Silencing of MTA1 gene as a strategy to inhibit tumor angiogenesis and metastasis; Role in breast cancer therapy

Prof. Bharathi.P Salimath

DBT

53.17

2009-2012

12.    Management of vegetable disease in North eastern region of India (Multicentric research project)

Prof. S.R Niranjana

DBT

63

2010-2013

13.    Production of scFv for Human sFlt-1 and sTie-2 : TRAIL fusion proteins with selective binding and apoptotic potential using Immunoliposomes

Prof.Bharathi.P

Salimath

DBT- Indo German

65.62

2010-2013

14.    Production of monoclonal antibodies and construction of scFv for a novel pro-angiogenic protein

Prof.Bharathi.P

Salimath

ICMR

6.39

2010-2013

15.    Diversity and Bioprospecting of endophytes from medicinal plants of endophytes

Prof. H. S. Prakash

MHRD-UGC

10

2009-2012

16.    Bioprospecting, high throughput screening  and advanced propagation of medicinal plants for anti- cancer agents

Prof.Bharathi.P

Salimath

MHRD-UGC

10

2009-2012

17.    Microbial diversity of western ghats with special reference to PGPR

Prof. S. R. Niranjana

MHRD-UGC

10

2009-2012

18.    Potential analysis of heat shock proteins for bioprospecting of medicinal plants in model systems

Dr. H. S. Aparna

MHRD-UGC

10

2009-2012

19.    Genetic and metabolic profiling of Medicinal plants

Dr. K. Ramachandra Kini

MHRD-UGC

10

2009-2012

20.    In vitro conservation of medicinal plants and their bioactivity

Dr. Geetha N. Prashanth

MHRD-UGC

10

2009-2012

21.    All India Coordinated Pearl Millet Improvement Project - Mysore Centre

Prof. H. S. Shetty

ICAR

60

2002-2012

 

7.      Any other Information:

Infrastructural Facilities available

Major Equipments

  • Electron Microscope
  • Phosphor Image Analyser for fluorescence and chemiluminescence detection
  • Ultra centrifuge
  • Spectramax Plate reader
  • Image analysis system
  • Gradient PCR machine
  • Realtime PCR machine
  • Microscopes
    • Epifluorescence, phase contrast, stereo binocular with digital imaging
    • Inverted Trinocular with CCD Camera
  • Pulse field gel electrophoresis system
  • Deep freezers (-80oC
  • HPLC System
  • UV-Visible Spectrophotometers
  • NanoSpectrophotometer
  • High Speed Refrigerated Centrifuge
  • Microplate Luminometer (Orion)
  • Multilabel Plate Reader
  • Liquid Scintillation Counter
  • CO2 incubators

Other infrastructural facilities

  • Well equipped Molecular Biology Laboratories
  • Radioisotope laboratory
  • Cold room, climate controlled rooms
  • International Seed Health Training Center
  • Computational and networking facilities
  • Departmental Library
  • Back-up power generator facilities
  • Green House and Screen House facilities
  • Plant Tissue Culture and animal cell culture facilities
  • Sick-plot to screen the cultivars of pearl millet, sorghum, maize and sunflower for downy mildew disease
  • International Guest House sponsored by DANIDA
  • Vehicles: Toyota Qualis- 1 and Canter (18 seater)- 1

   14. Contact :

         Chairman

         Telephone No.+91-821-2419877